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Though very rare, hyperacute cases are usually caused by Neisseria gonorrhoeae or N. Chronic cases of bacterial conjunctivitis are those lasting longer than 3 weeks, and are typically caused by Staphylococcus aureus, Moraxella lacunata, or gram-negative enteric flora.
Conjunctivitis may also be caused by allergens such as pollen, perfumes, cosmetics, smoke, Conjunctivitis is part of the triad of reactive arthritis, which is thought to be caused by autoimmune cross-reactivity following certain bacterial infections.
Reactive arthritis is highly associated with HLA-B27.
Conjunctivitis is associated with the autoimmune disease relapsing polychondritis.
With some chemicals, above all with caustic alkalis such as sodium hydroxide, there may be necrosis of the conjunctiva with a deceptively white eye due to vascular closure, followed by sloughing of the dead epithelium.